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Acod1/itaconate activates Nrf2 in pulmonary microvascular endothelial cells to guard versus the being overweight-induced pulmonary microvascular endotheliopathy Li ZhuPlasma and brains have been collected at the conclusion of the analyze. Baseline teams of naïve (untreated) rTg4510 mice were being also sacrificed at 8 or 12 months of age (n = 1